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Lionel A Tintignac Selected Research

Eukaryotic Initiation Factor-3

2/2009MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines.
6/2008eIF3-f function in skeletal muscles: to stand at the crossroads of atrophy and hypertrophy.
4/2008The initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy.

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Lionel A Tintignac Research Topics

Disease

5Hypertrophy
01/2020 - 04/2008
5Muscular Atrophy (Muscle Atrophy)
01/2020 - 04/2008
4Atrophy
01/2020 - 04/2008
3Neoplasms (Cancer)
06/2008 - 02/2002
2Muscular Diseases (Myopathy)
01/2020 - 05/2013
2Acquired Immunodeficiency Syndrome (AIDS)
06/2008 - 04/2008
1Sarcopenia
01/2020
1Insulin Resistance
11/2015
1Lipodystrophy
11/2015
1Body Weight (Weight, Body)
11/2015
1Starvation
05/2013
1Tuberous Sclerosis (Bourneville's Disease)
03/2013
1Renal Insufficiency (Renal Failure)
06/2008
1Sepsis (Septicemia)
04/2008
1Bloom Syndrome
02/2002

Drug/Important Bio-Agent (IBA)

6Mechanistic Target of Rapamycin Complex 1IBA
01/2020 - 02/2010
3Eukaryotic Initiation Factor-3IBA
02/2009 - 04/2008
2Peptide Initiation Factors (Initiation Factor)IBA
02/2009 - 04/2008
2Proteasome Endopeptidase Complex (Proteasome)IBA
02/2009 - 04/2008
2Proteins (Proteins, Gene)FDA Link
06/2008 - 04/2008
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
06/2008 - 04/2008
1Sirolimus (Rapamycin)FDA Link
01/2020
1Fatty Acids (Saturated Fatty Acids)IBA
11/2015
1fibroblast growth factor 21IBA
11/2015
1UbiquitinIBA
03/2013
1Ligases (Synthetase)IBA
03/2013
1trans-sodium crocetinate (crocetin)IBA
03/2013
1Phosphotransferases (Kinase)IBA
02/2010
1Muscle Proteins (Muscle Protein)IBA
06/2008
1Small Interfering RNA (siRNA)IBA
04/2008
1DNA HelicasesIBA
02/2002

Therapy/Procedure

1Denervation
03/2013